Faculty
Hormone response and treatment resistance in breast and ovarian cancer, including the analysis of aberrant genetic and epigenetic changes
*Currently accepting Graduate Students
We use Drosophila, iPSC models, mouse models, and human patient datasets to identify new therapeutic targets for Parkinson’s disease and related disorders.
The Opresko lab aims to develop novel strategies that preserve telomeres in healthy cells and delay aging-related diseases including cancer, or that conversely target telomeres to stop proliferation in cancer cells.
*Currently accepting graduate students
Spermatogonial stem cells (SSCs) and male germ lineage development
*Currently accepting Graduate Students
Our group extracts biological insights and disease mechanisms from multiomics data including single-cell and spatially resolved data.
*Currently accepting Graduate Students
Dr. Overacre is an Assistant Professor within the Department of Immunology at the University of Pittsburgh and a member of the Tumor Microenvironment Center (TMC) at the UPMC Hillman Cancer Center. Her laboratory is centered around understanding how the microbiota and immune system interact and contribute to anti-tumor immunity, immunotherapy, and immune-related adverse events. Specifically, they assess how external factors that shape the gut microbiome, including diet, impact T cell responses across cancer types in both preclinical models and patient samples.
*Currently accepting graduate students
The O’Sullivan lab at the Hillman Cancer Center conducts research into proteins that alter the structural and epigenetic functions of human telomeres.
*Currently accepting Graduate Students