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Trainee Name: Donald Bourne
Trainee: Current
Faculty Member: Lindsay Sabik, PhD

Donald S Bourne, Eric T Roberts, Lindsay M Sabik, Early Impacts of the Pennsylvania Rural Health Model on Potentially Avoidable Utilization, Health Affairs Scholar, 2024;, qxae002,

Bourne DS, Davis BS, Gigli KH, Chang CH, Yabes JG, Martsolf GR, Kahn JM. Economic Analysis of Mandated Protocolized Sepsis Care in New York Hospitals. Crit Care Med. 2020 Oct;48(10):1411-1418. doi: 10.1097/CCM.0000000000004514. PMID: 32931187.

Trainee Name: Wesley Brown PhD
Trainee: Current
Faculty Member: Alex Deiters, PhD

Cell Lineage Tracing in Zebrafish Embryos with an Expanded Genetic Code Brown, W.; Liu, J.; Tsang, M.; Deiters, A. ChemBioChem 2018, 19, 1244-1249. Highlighted as a Very Important Paper by ChemBioChem.

Light-Activation of Cre Recombinase in Zebrafish Embryos through Genetic Code Expansion, Brown, W.; Deiters, A. Methods Enzym. 2019, 624, 265-281.

Zhou W, Brown W, Bardhan A, Delaney M, Ilk AS, Rauen RR, Kahn SI, Tsang M, Deiters A. Spatiotemporal Control of CRISPR/Cas9 Function in Cells and Zebrafish using Light-Activated Guide RNA. Angew Chem Int Ed Engl. 2020 Jun 2;59(23):8998-9003. doi: 10.1002/anie.201914575. Epub 2020 Apr 6. PMID: 32160370; PMCID: PMC7250724.

Brown W, Liu J, Deiters A. Genetic Code Expansion in Animals. ACS Chem Biol. 2018;13(9):2375-86. Epub 2018/08/21. doi: 10.1021/acschembio.8b00520. PubMed PMID: 30125487; PMCID: PMC7026698.

Brown W, Zhou W, Deiters A. Regulating CRISPR/Cas9 Function through Conditional Guide RNA Control. Chembiochem. 2021;22(1):63-72. Epub 2020/08/25. doi: 10.1002/cbic.202000423. PubMed PMID: 32833316.

Zhou, W., Brown, W., Bardhan, A., Tsang, M., & Deiters, A. (2021). Optical Control of Base Editing and Transcription through Light‐Activated Guide RNA. ChemPhotoChem, 5(11), 984-988.

Brown, W., Bardhan, A., Darrah, K., Tsang, M., & Deiters, A. (2022). Optical Control of MicroRNA Function in Zebrafish Embryos. Journal of the American Chemical Society, 144(37), 16819-16826.

Brown, W., Albright, S., Tsang, M., & Deiters, A. (2022). Optogenetic Protein Cleavage in Zebrafish Embryos. ChemBioChem, e202200297.

Brown, W., Galpin, J. D., Rosenblum, C., Tsang, M., Ahern, C. A., & Deiters, A. (2023). Chemically Acylated tRNAs are Functional in Zebrafish Embryos. Journal of the American Chemical Society.

Brown, W., Wesalo, J., Tsang, M., & Deiters, A. (2023). Engineering small molecule switches of protein function in zebrafish embryos. Journal of the American Chemical Society, 145(4), 2395-2403.

Brown, W., Rosenblum, C., & Deiters, A. (2023). Small-Molecule Phosphine Activation of Protein Function in Zebrafish Embryos with an Expanded Genetic Code. In Genetically Incorporated Non-Canonical Amino Acids: Methods and Protocols (pp. 247-263). New York, NY: Springer US.

Brown, W., Wesalo, J., Samanta, S., Luo, J., Caldwell, S. E., Tsang, M., & Deiters, A. (2023). Genetically Encoded Aminocoumarin Lysine for Optical Control of Protein–Nucleotide Interactions in Zebrafish Embryos. ACS Chemical Biology.

Trainee Name: Ansen Burr PhD
Trainee: Current
Faculty Member: Timothy Hand, Ph.D.

Overacre-Delgoffe A.E., Cillo A.R., Bumgarner H.J., Burr A.H.P., Tometich J.T., Bhattacharjee A., Bruno T.C., Vignali D.A.A. and T.W. Hand. Microbiome-specific T follicular helper cells drive tertiary lymphoid structures and anti-tumor immunity against colorectal cancer 2021. Immunity. 2021 Dec 14;54(12):2812-2824.e4. doi: 10.1016/j.immuni.2021.11.003.

Van Der Kraak L.A., Schneider C., Dang V., Burr A.H.P., Weiss E.S., Hand T.W. and S.W. Canna Genetic and commensal induction of Interleukin-18 drive intestinal epithelial MHC class II via Interferon-g. Mucosal Immunology. 2021 Jun 8.  doi: 10.1038/s41385-021-00419-1

Bhattacharjee A., Burr A.H.P., Overacre-Delgoffe A.E., Tometich J.T., Yang D., Huckestein B.R., Linehan J.L., Spencer S.P., Hall J.A., Harrison O.J., Fonseca D.M., Norton, E.B., Belkaid Y. and T.W. Hand. Environmental Enteric Dysfunction induces intestinal regulatory T cells that inhibit local CD4+ T cell responses and impair the efficacy of oral vaccines. Immunity. 2021 Aug 10;54(8):1745-1757 PMID: 34348118

Gopalakrishna KP, Macadangdang BR, Rogers MB, Tometich JT, Firek BA, Baker R, Ji J, Burr AHP, Ma C, Good M, Morowitz MJ, Hand TW. Maternal IgA protects against the development of necrotizing enterocolitis in preterm infants. Nat Med. 2019 Jul;25(7):1110-1115. doi: 10.1038/s41591-019-0480-9. Epub 2019 Jun 17. PMID: 31209335

Castillo-Dela Cruz P, Wanek AG, Kumar P, An X, Elsegeiny W, Horne W, Fitch A, Burr AHP, Gopalakrishna KP, Chen K, Methé BA, Canna SW, Hand TW, Kolls JK. Intestinal IL-17R Signaling Constrains IL-18-Driven Liver Inflammation by the Regulation of Microbiome-Derived Products. Cell Rep. 2019 Nov 19;29(8):2270-2283.e7. doi: 10.1016/j.celrep.2019.10.042. PMID: 31747600; PMCID: PMC6886715.

Burr AHP, Bhattacharjee A, Hand TW. Nutritional Modulation of the Microbiome and Immune Response. J Immunol. 2020 Sep 15;205(6):1479-1487. doi: 10.4049/jimmunol.2000419. PMID: 32900885; PMCID: PMC7490768

Trainee Name: Alison Butler PhD
Trainee: Current
Faculty Member: Gretchen Chapman, PhD

Butler A, Chapman GB. Don't Throw Your Heart Away: Increased Transparency of Donor Utilization Practices in Transplant Center Report Cards Alters How Center Performance Is Evaluated. Med Decis Making. 2022 Apr;42(3):341-351. doi: 10.1177/0272989X211038941. Epub 2021 Oct 4. PMID: 34605713.

Godown J, Butler A, Lebovitz DJ, Chapman G. Predictors of Deceased Organ Donation in the Pediatric Population. Pediatrics. 2021 Jun;147(6):e2020009506. doi: 10.1542/peds.2020-009506. Epub 2021 May 7. PMID: 33963074;.

Butler A, Chapman G, Johnson JN, Amodeo A, Böhmer J, Camino M, Davies RR, Dipchand AI, Godown J, Miera O, Pérez-Blanco A, Rosenthal DN, Zangwill S, Kirk R. Behavioral economics-A framework for donor organ decision-making in pediatric heart transplantation. Pediatr Transplant. 2020 May;24(3):e13655. doi: 10.1111/petr.13655. Epub 2020 Jan 27. PMID: 31985140.

Godown J, Schumacher KR, Butler A, Chapman G, Dipchand AI, Kaslow WW, Bearl DW, Kirk R. Patients and their family members prioritize post-transplant survival over waitlist survival when considering donor hearts for transplantation. Pediatr Transplant. 2020;24(2):e13589. Epub 2019/09/29. doi: 10.1111/petr.13589. PubMed PMID: 31562687    

Godown J, Schumacher KR, Butler A, Chapman G, Dipchand AI, Kaslow WW, Bearl DW, Kirk R. Patients and their family members prioritize post-transplant survival over waitlist survival when considering donor hearts for transplantation. Pediatr Transplant. 2020 Mar;24(2):e13589. doi: 10.1111/petr.13589. Epub 2019 Sep 27. PMID: 31562687.

Kirk R, Dipchand AI, Davies RR, Miera O, Chapman G, Conway J, Denfield S, Gossett JG, Johnson J, McCulloch M, Schweiger M, Zimpfer D, Ablonczy L, Adachi I, Albert D, Alexander P, Amdani S, Amodeo A, Azeka E, Ballweg J, Beasley G, Böhmer J, Butler A, Camino M, Castro J, Chen S, Chrisant M, Christen U, Danziger-Isakov L, Das B, Everitt M, Feingold B, Fenton M, Garcia-Guereta L, Godown J, Gupta D, Irving C, Joong A, Kemna M, Khulbey SK, Kindel S, Knecht K, Lal AK, Lin K, Lord K, Möller T, Nandi D, Niesse O, Peng DM, Pérez-Blanco A, Punnoose A, Reinhardt Z, Rosenthal D, Scales A, Scheel J, Shih R, Smith J, Smits J, Thul J, Weintraub R, Zangwill S, Zuckerman WA. ISHLT consensus statement on donor organ acceptability and management in pediatric heart transplantation. J Heart Lung Transplant. 2020 Apr;39(4):331-341. doi: 10.1016/j.healun.2020.01.1345. Epub 2020 Jan 31. PMID: 32088108.

Trainee Name: Neil Carleton
Trainee: Current
Faculty Member: Adrian Lee, PhD

Carleton, N., Abidi, H., Puthanmadhom-Narayanan, S., Marroquin, O. C., Oesterreich, S., Diego, E. J., Brufsky, A. M., Lee, A. V., & McAuliffe, P. F. (2023). Omission of surgery, primary endocrine therapy adherence, and effect of comorbidity in older women with estrogen receptor positive breast cancer. Journal of Geriatric Oncology, 101679–101679.

Steffi Oesterreich, PhD, Azadeh Nasrazadani, MD, PhD, Jian Zou, MS, Neil Carleton, BS, Tiffany Onger, MD, Matthew D Wright, MD, Yujia Li, BS, Kathryn Demanelis, PhD, Bhuvaneswari Ramaswamy, MD, George Tseng, PhD, Adrian V Lee, PhD, Nicole Williams, MD, Megan Kruse, MD, Clinicopathological Features and Outcomes Comparing Patients With Invasive Ductal and Lobular Breast Cancer, JNCI: Journal of the National Cancer Institute, 2022;, djac157,

Carleton, N., McAuliffe, P.F. Are the chronological age cutoffs used in clinical oncology guidelines biologically meaningful?. Nat Rev Clin Oncol (2022).

Carleton N, Nasrazadani A, Gade K, Beriwal S, Barry PN, Brufsky AM, Bhargava R, Berg WA, Zuley ML, Marroquin OC, Thull DL, Mai PL, Diego EJ, Lotze MT, Oesterreich S, McAuliffe PF, Lee AV. Personalizing Therapy for Early-Stage ER+ Breast Cancer in Older Women. The Lancet Healthy Longevity. 2021 Nov 9. In Press.
Carleton N, Zou J, Fang Y, Koscumb SE, Shah OS, Chen F, Beriwal S, Diego EJ, Brufsky AM, Oesterreich S, Shapiro SD, Ferris R, Emens LA, Tseng G, Marroquin OC, Lee AV, McAuliffe PF. Outcomes After Sentinel Lymph Node Biopsy and Radiotherapy in Older Women With Early-Stage, Estrogen Receptor-Positive Breast Cancer. JAMA Netw Open. 2021 Apr 1;4(4):e216322. doi: 10.1001/jamanetworkopen.2021.6322. PubMed PMID: 33856473; PubMed Central PMCID: PMC8050744.
Lee JL, Ekambaram P, Carleton NM, Hu D, Klei LR, Cai Z, Myers MI, Hubel NE, Covic L, Agnihotri S, Krappmann D, Bornancin F, Lee AV, Oesterreich S, McAllister-Lucas L, Lucas PC. MALT1 is a Targetable Driver of Epithelial-to-Mesenchymal Transition in Claudin-low, Triple-Negative Breast Cancer. Mol Cancer Res. 2021 Nov 9;. doi: 10.1158/1541-7786.MCR-21-0208. [Epub ahead of print] PubMed PMID: 34753803.
Chen F, Ding K, Priedigkeit N, Elangovan A, Levine KM, Carleton N, Savariau L, Atkinson JM, Oesterreich S, Lee AV. Single-Cell Transcriptomic Heterogeneity in Invasive Ductal and Lobular Breast Cancer Cells. Cancer Res. 2021 Jan 15;81(2):268-281. doi: 10.1158/0008-5472.CAN-20-0696. Epub 2020 Nov 4. PubMed PMID: 33148662; PubMed Central PMCID: PMC7856056.
Ghosh-Choudhary S, Carleton N, Flynn JL, Kliment CR. Strategies for Achieving Gender Equity and Work-Life Integration in Physician-Scientist Training. Acad Med. 2021 Jul 20;. doi: 10.1097/ACM.0000000000004246. [Epub ahead of print] PubMed PMID: 34292189.


Trainee Name: Brittany Chamberlain
Trainee: Current
Faculty Member: Susanne Ahmari, MD, PhD

Chamberlain B.L., Ahmari S.E. (2021) Animal Models for OCD Research. In: Fineberg N.A., Robbins T.W. (eds) The Neurobiology and Treatment of OCD: Accelerating Progress. Current Topics in Behavioral Neurosciences, vol 49. Springer, Cham.

Piantadosi SC, McClain LL, Klei L, Wang J, Chamberlain BL, Springer SA, Lewis DA, Devlin B, Ahmari SE. Transcriptome alterations are enriched for synapse-associated genes in the striatum of subjects with obsessive-compulsive disorder. Transl Psychiatry. 2021 Mar 15;11(1):171. doi: 10.1038/s41398-021-01290-1. PMID: 33723209; PMCID: PMC7961029.

Piantadosi SC, Chamberlain BL, Glausier JR, Lewis DA, Ahmari SE. Lower excitatory synaptic gene expression in orbitofrontal cortex and striatum in an initial study of subjects with obsessive compulsive disorder. Mol Psychiatry. 2021 Mar;26(3):986-998. doi: 10.1038/s41380-019-0431-3. Epub 2019 Jun 5. PMID: 31168067.

Trainee Name: Jonathan Cohen PhD
Trainee: Current
Faculty Member: Daniel Kaplan, MD, PhD

Huang H, Kuzirian MS, Cai X, Snyder LM, Cohen J, Kaplan DH, Ross SE. Generation of a NK1R-CreER knockin mouse strain to study cells involved in Neurokinin 1 Receptor signaling. Genesis. 2016 Nov;54(11):593-601. doi: 10.1002/dvg.22985. Epub 2016 Oct 31. PMID: 27712014; PMCID: PMC5241089.

Cohen JA, Edwards TN, Liu AW, Hirai T, Jones MR, Wu J, Li Y, Zhang S, Ho J, Davis BM, Albers KM, Kaplan DH. Cutaneous TRPV1+ Neurons Trigger Protective Innate Type 17 Anticipatory Immunity. Cell. 2019 Aug 8;178(4):919-932.e14. doi: 10.1016/j.cell.2019.06.022. Epub 2019 Jul 25. PMID: 31353219; PMCID: PMC6788801.

Cohen JA, Wu J, Kaplan DH. Neuronal Regulation of Cutaneous Immunity. J Immunol. 2020 Jan 15;204(2):264-270. doi: 10.4049/jimmunol.1901109. PMID: 31907268; PMCID: PMC7583491.

Saloman JL, Cohen JA, Kaplan DH. Intimate neuro-immune interactions: breaking barriers between systems to make meaningful progress. Curr Opin Neurobiol. 2020 Jun;62:60-67. doi: 10.1016/j.conb.2019.11.021. Epub 2019 Dec 13. PMID: 31841783.

Trainee Name: Raphael Crum PhD
Trainee: Current
Faculty Member: Stephen Badylak, MD, PhD

Crum RJ, Johnson SA, Jian P, et. Al. Transcriptomic, Proteomic, and Morphologic Characterization of Healing in Volumetric Muscle Loss. Tissue Engineering Part A. Accepted July 2022.

Crum RJ, Capella-Monsonis H, Badylak SF, Hussey G. Extracellular Vesicles for Regenerative Medicine Applications. Submitted to Applied Sciences. July 25, 2022.

Crum RJ, Hall K, Pineda C, Hussey G, Graham E, Li H, Badylak SF. Immunomodulatory matrix-bound nanovesicles mitigate acute and chronic pristane-induced rheumatoid arthritis. npj Regenerative Medicine. February 2, 2022.

Crum RJ, Kay J, et. Al. Bone vs All Soft Tissue Quadriceps Tendon Autografts for Anterior Cruciate Ligament Reconstruction: A Systematic Review. Arthroscopy. October 21, 2020.

Crum RJ, Hussey G, Saldin L, Dziki J, Badylak SF. Development of a colloidal, extracellular matrix hydrogel for the operative management of simple and complex anorectal fistulas. Gastroenterology. May 2020.

Hussey G, (…6…) Crum RJ, (…), Badylak SF. Ultrasonic Cavitation to prepare ECM hydrogels. Acta Biomaterialia. March 2020.

Do Amaral MCF, Frisbie J, Crum RJ, Goldstein DL, Krane CM. Hepatic transcriptome of the freeze-tolerant Cope’s gray treefrog, Dryophytes chrysoscelis: responses to cold acclimation and freezing. BMC Genomics. March 2020.

de SA D, Crum RJ, Rabuck S, et. Al. The REVision using Imaging to guide Staging and Evaluation (REVISE) in ACL Reconstruction Classification. Journal of Knee Surgery. (Accepted Aug 12, 2019)

Zhang K, Crum RJ, Samuelsson K, Cadet E, Ayeni OR, de SA D. In-office needle arthroscopy: A systematic review of indications and clinical utility. Arthroscopy. Aug 12, 2019.

Crum RJ, de SA D, Su FL, Lesniak BP, Lin A. Decreased complication profile and improved clinical outcomes of primary reverse total shoulder arthroplasty after 2010: A systematic review. Shoulder and Elbow. June 2019.

Crum RJ, de SA D, Kanakamedala A, Obioha O, Lesniak BP, Musahl V. Aperture and suspensory fixation equally efficacious for quadriceps tendon graft fixation in primary ACL reconstruction: A systematic review. Journal of Knee Surgery. April 2019.

De SA D, Arakgi M, Lian J, Crum RJ, Lin A, Lesniak BP. Labral repair versus biceps tenodesis for primary isolated type II SLAP tears: A systematic review. Arthroscopy. March 2019.

Crum RJ, de SA D, Ayeni OR, et al. No difference between extraction drilling and serial dilation for tibial tunnel preparation in anterior cruciate ligament reconstruction: a systematic review. Journal of ISAKOS: Joint Disorders & Orthopaedic Sports Medicine. 20 February 2018. 

Trainee Name: Samuel Dienel PhD
Trainee: Current
Faculty Member: David Lewis, MD

Dienel SJ, Bazmi HH, Lewis DA. Development of transcripts regulating dendritic spines in layer 3 pyramidal cells of the monkey prefrontal cortex: Implications for the pathogenesis of schizophrenia. Neurobiol Dis. 2017 Sep;105:132-141. doi: 10.1016/j.nbd.2017.05.016. Epub 2017 May 31.

Hoftman GD, Dienel SJ, Bazmi HH, Zhang Y, Chen K, Lewis DA. Altered Gradients of Glutamate and Gamma-Aminobutyric Acid Transcripts in the Cortical Visuospatial Working Memory Network in Schizophrenia. Biol Psychiatry. 2018 Apr 15;83(8):670-679. doi: 10.1016/j.biopsych.2017.11.029. Epub 2017 Dec 7.

Dienel SJ, Lewis DA. Alterations in cortical interneurons and cognitive function in schizophrenia. Neurobiol Dis. 2019 Nov;131:104208. doi: 10.1016/j.nbd.2018.06.020. Epub 2018 Jun 22.

Dienel SJ, Enwright JF 3rd, Hoftman GD, Lewis DA. Markers of glutamate and GABA neurotransmission in the prefrontal cortex of schizophrenia subjects: Disease effects differ across anatomical levels of resolution. Schizophr Res. 2020 Mar;217:86-94. doi: 10.1016/j.schres.2019.06.003. Epub 2019 Jul 8.

Schoonover KE, Dienel SJ, Lewis DA. Prefrontal cortical alterations of glutamate and GABA neurotransmission in schizophrenia: Insights for rational biomarker development. Biomark Neuropsychiatry. 2020 Dec;3:100015. doi: 10.1016/j.bionps.2020.100015. Epub 2020 May 18.

Trainee Name: George Gabriel PhD
Trainee: Current
Faculty Member: Cecilia Lo, PhD

Gabriel GC, Pazour GJ, Lo CW. Congenital Heart Defects and Ciliopathies Associated With Renal Phenotypes. Front Pediatr. 2018 Jun 15;6:175. doi: 10.3389/fped.2018.00175. eCollection 2018.

Gabriel GC, Young CB, Lo CW. Role of cilia in the pathogenesis of congenital heart disease. Semin Cell Dev Biol. 2020 May 14:S1084-9521(19)30166-1. doi: 10.1016/j.semcdb.2020.04.017. Online ahead of print.

Gabriel GC, Lo   CW. Left-right patterning in congenital heart disease beyond heterotaxy. Am J Med Genet C Semin Med Genet. 2020 Mar;184(1):90-96. doi: 10.1002/ajmg.c.31768. Epub 2020 Jan 30.