Congratulations to Talia Adi, winner of the first-place prize in the School of Medicine’s edition of the 2025 Three Minute Thesis (3MT) competition, and to Britt Chamberlain and Aidan Cole who tied for runner-up....
News
Post Date:
04-04-2025
Post Date:
02-18-2025
Post Date:
01-31-2025
Itch is a dominant symptom in dermatitis, and scratching promotes cutaneous inflammation, thereby worsening disease. However, the mechanisms through which scratching exacerbates inflammation and whether scratching provides benefit to the host are...
Post Date:
01-25-2025
Nathalie Chen earns the prestigious American Heart Association Predoctoral Fellowship. Congratulations, Nathalie!
Post Date:
01-16-2025
Female individuals who are post-menopausal present with higher incidence of knee osteoarthritis (KOA) than male counterparts; however, the mechanisms underlying this disparity are unknown. The most commonly used preclinical models lack human...
Post Date:
01-13-2025
Background: Pulmonary arterial hypertension (PAH) is a deadly disease without effective non-invasive diagnostic and prognostic testing. It remains unclear whether vasodila...
Post Date:
12-26-2024
Background: People with Alzheimer's disease (AD) exhibit varying clinical trajectories. There is a need to predict future AD-related outcomes such as morbidity and mortali...
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12-12-2024
First-line immune checkpoint inhibitor (ICI) combinations show responses in subsets of hepatocellular carcinoma (HCC) patients. Nearly half of HCCs are Wnt-active with mutations in CTNNB1 (encoding for β-catenin), AXIN1/2, or...
Post Date:
12-10-2024
Rachael A. Gordon, assistant professor of medicine, was awarded the Distinguished Fellow Award from the Association of Rheumatology Professionals, a division of the American College of Rheumatology. The award reflects her outstanding contributions to...
Post Date:
12-09-2024
MSTP student Lily Bessette’s paper on the generalizability of clinical trials behind the 2017 ACC/AHA blood pressure guidelines was recently published in JAMA Internal Medicine. The study examines the applicability of these trials to diverse patient...
Post Date:
11-08-2024
Transcriptomic analyses have advanced the understanding of complex disease pathophysiology including chronic obstructive pulmonary disease (COPD). However, identifying relevant biologic causative factors has been limited by the integration of high...
Post Date:
11-01-2024
Resting heart rate may confer risk for cardiovascular disease (CVD) and other adverse cardiovascular events. While the brainstem's autonomic control over heart rate is well established, less is known about the regulatory role of higher level corti...
Post Date:
10-23-2024
Morgan L. Egnot, MS, received the PFD Week 24 Best Resident/Student Paper Award for their manuscript, "Vaginal Extracellular Matrix-derived Hydrogel: The Future of Vaginoplasty." The award recognizes Egnot's pioneering research on the use of extracel...
Post Date:
10-01-2024
Immunosenescence is a well-characterized phenomenon that occurs with increasing age in all immune and somatic cells. In order to best study immunosenescence, it is imperative to develop methods to accurately identify immunosenescent cells. Elderly...
Post Date:
10-01-2024
Importance: Choosing Wisely recommendations advocate against routine use of axillary staging in older women with early-stage, clinically node-negative (cN0), hormone receptor-positive (HR+), and HER2-negative breast cancer. Howev...
Post Date:
09-24-2024
Alzheimer's disease (AD) and more than twenty other dementias, termed tauopathies, are pathologically defined by insoluble aggregates of the microtubule-associated protein tau (MAPT). Although tau aggregation correlates with AD symptomology, the s...
Post Date:
08-01-2024
Alzheimer disease (AD) and obesity are related to disruptions in the white matter (WM) connectome. We examined the link between the WM connectome and obesity and AD through edge-density imaging/index (EDI), a tractography-based method that charact...
Post Date:
07-29-2024
Traumatic brain injury (TBI) remains a leading cause of death and disability that places a great physical, social, and financial burden on individuals and the health system. In this review, we summarize new research into the metabolic changes desc...
Post Date:
07-01-2024
Permanent supportive housing (PSH) programs, which have grown over the last decade, have been associated with changes in health care utilization and spending. However, little is known about the impact of such programs on use of prescription drugs...
Post Date:
07-01-2024
Copper is a critical trace element in biological systems due the vast number of essential enzymes that require the metal as a cofactor, including cytochrome c oxidase, superoxide dismutase and dopamine-β-hydroxylase. Due its key role in oxidative...
Post Date:
06-21-2024
Precision management of fibrotic lung diseases is challenging due to their diverse clinical trajectories and lack of reliable biomarkers for risk stratification and therapeutic monitoring. Here, we validated the accuracy of CMKLR1 as an imaging bi...
Post Date:
05-28-2024
The fundamental steps in high-grade serous ovarian cancer (HGSOC) initiation are unclear, thus providing critical barriers to the development of prevention or early detection strategies for this deadly disease. Increasing evidence demonstrates mos...
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05-22-2024
Ugonna Mbaekwe - received both the NHLBI Diversity Supplement Award and an Outstanding Abstract Award at American Thoracic Society International Conference in May 2024
Post Date:
05-17-2024
Matthew Eric Piraino Awards for Excellence in Infectious Disease
This award is to be given to a fourth-year medical student with an interest in infectious diseases. This year’s award is presented to Alexander Layden
...
Post Date:
05-08-2024
Purpose: Natural language understanding (NLU) may be particularly well equipped for enhanced data capture from the electronic health record given its examination of both c...
Post Date:
04-06-2024
Lloyd Harvey, MD, PhD (Pitt/CMU MSTP alumni) won the Young Investigator Award in Basic & Translational Science at ACC!
Post Date:
04-01-2024
The role of neurogenesis in neurodevelopmental disorders (NDDs) merits much attention. The complex process by which stem cells produce daughter cells that in turn differentiate into neurons, migrate various distances, and form synaptic connections...
Post Date:
04-01-2024
Background: Although cardiac rehabilitation (CR) has established benefits for cardiovascular health, it remains significantly underutilized, with substantial differences i...
Post Date:
03-12-2024
Congratulations to Gabby Gilmer on achieving 3rd place in the Poster Presentation at AR3T-Alliance for Regenerative Rehabilitation Research & Training!...
Post Date:
02-29-2024
Dr. Mehret Birru Talabi from @PittRheum...
Post Date:
02-06-2024
Background: The coronavirus disease 2019 (COVID-19) pandemic has negatively affected the social fabric.
Objective: We evaluated the associations...
Post Date:
02-02-2024
Anna Kirillova wins the prestigious Rupert Swift Award at the Pulmonary Vascular Research Institute annual meeting in London, England.
Post Date:
01-31-2024
In brain, the striatum is a heterogenous region involved in reward and goal-directed behaviors. Striatal dysfunction is linked to psychiatric disorders, including opioid use disorder (OUD). Striatal subregions are divided based on neuroanatomy, ea...
Post Date:
01-30-2024
Most women ≥70 years undergo breast surgery for primary treatment of estrogen receptor (ER) positive breast cancer. Only a small minority forego surgical intervention despite a growing body of literature, mainly from the United Kingdom (UK) a...
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01-19-2024
The nature and extent of hemispheric lateralization and its potential for reorganization continues to be debated, although there is general agreement that there is a right hemisphere (RH) advantage for face processing in human adults. Here, we exa...
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01-19-2024
The Pennsylvania Rural Health Model (PARHM) is a novel alternative payment model for rural hospitals that aims to test whether hospital-based global budgets, coupled with delivery transformation plans, improve the quality of health care and health...
Post Date:
01-15-2024
Many important neurocognitive states, such as performing natural activities and fluctuations of arousal, shift over minutes-to-hours in the real-world. We harnessed 3-12 days of continuous multi-electrode intracranial recordings in twenty humans d...
Post Date:
01-07-2024
Resting heart rate may confer risk for cardiovascular disease (CVD) and other adverse cardiovascular events. While the brainstem's autonomic control over heart rate is well established, less is known about the regulatory role of higher-level corti...
Post Date:
11-06-2023
Congratulations to Gabby Gilmer, G3, for winning the Mininder S. Kocher Award for Most Promising Career from the Pediatric Research in Sports Medicine group
Post Date:
09-22-2022
A collaborative group of neuroscientists from Carnegie Mellon University and the University of Pittsburgh School of Medicine received a $6.8 million grant from the National Institutes of Health (NIH) Brain Research Through Advancing Innovative Neu...
Post Date:
01-25-2022
The MSTP students took the afternoon off to gather for an afternoon of ice skating. The weather was chilly but spirits were high and fun was had by all.
Post Date:
09-15-2021
The Local Chapter of the American Physician Scientists Association (APSA) at the University of Pittsburgh School of Medicine is hosting the 2022 APSA Northeast Regional Conference (NERC) on January 15-16, 2022. Our conference will include keynote spe...
Post Date:
09-01-2021
The Achievement Rewards for College Scientist Foundation (ARCS) is a national women’s organization, operating in 14 independent chapters across the country. The ARCS Foundation provides financial support in the form of awards to academically outstan...
Post Date:
07-30-2021
Last night at the retreat the rising MS1 class introduced themselves as the "Science Superheros!" We are so excited to welcome you to the Pitt/CMU MSTP and we can't wait to see what you accomplish!
Post Date:
07-26-2021
Opioids are a mainstay of treatment for pain worldwide. Pruritus, a common side effect of opioids, is a patient dissatisfier that limits their use in many clinical settings. Both parenteral and neuraxial administration of opioids frequently evoke pru...
Post Date:
07-20-2021
Substantial gender inequities persist across academic medicine. These issues are not new: Recent evidence still points to a chilly climate for women in academic medicine, including those in physician-scientist training. The discussion for how to addr...
Post Date:
07-10-2021
What a weekend! We finally were able to convene as an MSTP with a beautiful picnic outdoors at the wonderful Mellon Park @TheFrickPgh! It was great to see so many new and familiar faces! We look forward to gathering again as a group at the MSTP retre...
Post Date:
07-07-2021
Congratulations to Michael Granovetter for receiving the American Epilepsy Society Predoctoral Research Fellowship!
Post Date:
07-06-2021
Molina et al. demonstrate that loss of Yap1 in developing livers leads to absence of intrahepatic bile ducts, preventing bile secretion from liver to small intestines. Yap1 knockout mice are small and jaundiced and exhibit adaptation via altering bil...
Post Date:
07-06-2021
Tissue engineering utilizes our understanding of biomechanics, biomaterials, and biology to build tissues and organs from scratch for diagnostics and therapeutics. This approach has been leveled at clinical and research problems in all organ syste...
Post Date:
06-28-2021
Please join Pitt/CMU MSTP for Edgar's Thesis Defense titled "Towards patient specific direct cardiac compression" on June 28th at 1pm.
Join Zoom Meeting https://cmu.zoom.us/j/99613388722?pwd=U0RWZWJ1bU5sRDh1Yk95bENRcytqUT09
Meeting...
Post Date:
10-01-2020
From the article in The Journal of Clinical Investigation: Alarmins, sequestered self-molecules containing damage-associated molecular patterns, are released during tissue injury to drive innate immune cell proinflammatory responses. Whether endogeno...
Post Date:
09-24-2020
Eileen Nguyen took 1st place in the Society of Obstetric Anesthesia and Perinatology 2020 Virtual meeting in Best Basic Science Category. Congratulations, Eileen!
Post Date:
09-21-2020
Congratulations, Maria!
Post Date:
08-05-2020
Post Date:
07-27-2020
Abstract
Objectives:
Initial evidence suggests that state-level regulatory mandates for sepsis quality improvement are associated with decreased sepsis mortality. However, sepsis mandates require financial investments on...
Post Date:
07-01-2020
PITTSBURGH— Martial Hebert, dean of Carnegie Mellon University’s School of Computer Science, has named Russell Schwartz the new head of the Computational Biology Department, effective July 1.
Schwartz, a professor in both the Computational...
Post Date:
06-17-2020
From the Article In Cell Press: The lateral parabrachial nucleus (lPBN) is a majortarget of spinal projection neurons conveying noci-ceptive input into supraspinal structures. However,the functional role of distinct lPBN efferents indiverse nocife...
Post Date:
05-24-2020
From the article in Pediatric Transplant: The high discard rate of pediatric donor hearts presents a major challenge for children awaiting heart transplantation. Recent literature identifies several factors that contribute to the disparities in pe...
Post Date:
05-20-2020
Maxwell Wang was selected for one of the most prestigious awards of its kind, the Hertz Fellowship. This Fellowship supports five years of graduate research and the freedom to pursue innovative ideas, wherever they may lead. Hertz Fellows also rec...
Post Date:
04-03-2020
Congratulations to Philip for being awarded the 2020 Medical Student Research Grant: Discovering Molecular Imaging funded through the Society of Nuclear Medicine and Molecular Imaging.
Post Date:
03-23-2020
Congratulations to Oyin for this impressive achievement.
Post Date:
03-17-2020
Congratulations to Tolani for successfully defending your thesis!
Post Date:
03-06-2020
From the article in The Journal of Neuroscience: Autism spectrum disorder (ASD) is characterized partly by atypical attentional engagement, reflected in exaggerated and variable responses to sensory stimuli. Attentional engagement is known to be r...
Post Date:
02-26-2020
From the article in Journal of Neurophysiology: Separating neural signals from noise can improve brain-computer interface performance and stability. However, most algorithms for separating neural action potentials from noise are not suitable for u...
Post Date:
02-24-2020
Maria Ly successfully defended her Thesis on February 24, 2020. Congratulations Maria!
Post Date:
02-19-2020
From the article in Chemical Communications: Site-specific placement of unnatural amino acids, particularly those responsive to light, offers an elegant approach to control protein function and capture their fleeting ‘interactome’. Herein, we have...
Post Date:
01-25-2020
Gabby Gilmer presented her poster titled "Evaluation Of Serum Relaxin Concentrations And Knee Valgus After Anterior Cruciate Ligament Reconstruction" at the 7th Annual PRiSM Meeting in Glendale, Arizona.
Post Date:
01-23-2020
Increasing evidence implicates metabolic pathways as key regulators of cell fate and function. Although the metabolism of glucose, amino acids, and fatty acids is essential to maintain over...
Post Date:
01-01-2020
The tuberculosis vaccine has been around for nearly 100 years, but isn’t predictably effective against the deadly disease as currently administered. In the new study, Flynn and a large team of Pitt researchers, in collaboration with scientists from t...