Research Interests
The Gaffen lab takes a basic science approach to understand the molecular and cellular mechanisms that underline cytokine-mediated inflammation, whether for good (prevent infections) or bad (promote autoimmune pathology). Our main focus is IL-17, which is produced mainly by T cells and other lymphocytes. We study IL-17 in antifungal mucosal and systemic host defense, particularly in response to the commensal fungus Candida albicans.
*Currently accepting graduate students
Program
Molecular Genetics and Developmental Biology
Microbiology and Immunology