Sameer Agnihotri, PhD, is a tenured associate professor at the University of Pittsburgh Department of Neurological Surgery and serves as the director of the Brain Tumor Biology and Therapy Laboratory, based at UPMC Children’s Hospital of Pittsburgh. His research primarily investigates pediatric and adult high-grade gliomas (HGG), including diffuse intrinsic pontine gliomas (DIPG), with a significant focus on NF1-associated tumor biology and its implications for brain tumor progression. Through integrated genomic and metabolic analyses, Dr. Agnihotri's laboratory aims to develop accurate preclinical models of high-grade gliomas. These models are essential for testing novel therapies and facilitating early-phase clinical trials, ultimately striving toward personalized brain tumor treatments.
*Currently accepting graduate students