Research Interests
The Sun lab is interested in understanding the role of ion transporter proteins (Na+-K+ -Cl- cotransporter, Na+/H+ exchanger, and Na+/Ca2+ exchangers) in ionic dysregulation and neurodegeneration associated with stroke, traumatic brain injury, or glioma tumor. In particular, we study how changes of cytosolic ionic concentrations (Na+, H+, Ca2+) as well as organelle Ca2+ (ER and mitochondria) cause cell death and proinflammatory responses in ischemic or traumatic brain damage. We are also interested in studying Glioblastoma multiforme (GBM) brain tumor. We investigate how the Cl- cotransporter functions in regulation of intracellular Cl- and cell volume in GBM cancer cell survival and migration.
*Currently accepting graduate students
Program
Neuroscience (CNUP)