The Parthasarathy lab studies how the peripheral auditory system and the central auditory pathway interact in various forms of hearing loss. The research program integrates study of human clinical populations and animal models. In humans, we combine perceptual tasks with measures of listening effort (pupillometry) to assess behavioral and cognitive aspects of speech comprehension. In animal models we use neuronal recordings from various stages of the auditory pathway combined with immunohistology to inform mechanistic hypotheses. The overall goal is to inform diagnosis and track the benefits of interventional therapies in clinical populations with hearing loss by utilizing insights obtained from animal models with similar forms of pathology.
*Currently accepting graduate students